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Long Term Care Medicine-2011


B41 - Minding Your P450s: How to Recognize and Prevent Clinically Significant Drug Interactions in Long Term Care


Mar 25, 2011 11:00am ‐ Mar 25, 2011 12:00pm

Standard: $24.00

Description

Accreditation
The American Medical Directors Association (AMDA) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Designation Statement:
The American Medical Directors Association designates
this educational activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™.
Physicians should only claim credit commensurate with the extent of their participation in the activity.

AMDCP Credit Designation:
This session has been approved for a total of 1.0 Clinical credit hours toward certification as a Certified Medical Director in Long Term Care (CMD).

Session Description:
The majority of clinically significant drug interactions in long term care facilities involve alterations of one or more cytochrome P450 (CYP450) enzymes responsible for the metabolism of most drugs. CYP450 enzyme activity can be altered by either genetic variation (polymorphisms) or by commonly prescribed medications that either inhibit or enhance enzyme activity. The end result can be either an adverse reaction or loss of therapeutic response to the target drug. This session will provide practical information and guidance to enable physicians and other providers to recognize and prevent drug combinations that have the potential to significantly harm their patients. Cases will be used throughout to highlight common clinical scenarios encountered in long term care.

Learning Objectives(s):

  • Identify the most important CYP450 enzyme inhibitors and inducers responsible for many drug interactions.
  • Recognize the most common and clinically significant drug interactions occurring in clinical practice today.
  • Predict adverse drug reactions and therapeutic response based on the genetic polymorphism profile of CYP450 enzymes.
  • Interpret drug interaction tables to help guide therapeutic decisions.

Speakers(s):
Thomas Lynch, PharmD

Disclosure(s):
Thomas J. Lynch, PharmD has no financial disclosures to report.

Speaker(s):

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