Accreditation The American Medical Directors Association (AMDA) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Designation Statement: The American Medical Directors Association designates this educational activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
AMDCP Credit Designation: This session has been approved for a total of 1.0 Clinical credit hours toward certification as a Certified Medical Director in Long Term Care (CMD).
Session Description: The majority of clinically significant drug interactions in long term care facilities involve alterations of one or more cytochrome P450 (CYP450) enzymes responsible for the metabolism of most drugs. CYP450 enzyme activity can be altered by either genetic variation (polymorphisms) or by commonly prescribed medications that either inhibit or enhance enzyme activity. The end result can be either an adverse reaction or loss of therapeutic response to the target drug. This session will provide practical information and guidance to enable physicians and other providers to recognize and prevent drug combinations that have the potential to significantly harm their patients. Cases will be used throughout to highlight common clinical scenarios encountered in long term care.
Identify the most important CYP450 enzyme inhibitors and inducers responsible for many drug interactions.
Recognize the most common and clinically significant drug interactions occurring in clinical practice today.
Predict adverse drug reactions and therapeutic response based on the genetic polymorphism profile of CYP450 enzymes.
Interpret drug interaction tables to help guide therapeutic decisions.
Speakers(s): Thomas Lynch, PharmD
Disclosure(s): Thomas J. Lynch, PharmD has no financial disclosures to report.